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ABBV-744 - CAS# 2138861-99-9 48671 To test whether PK11007 also

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Description

To test whether PK11007 also increases ROS levels

PNU 100592

resulting in high selectivity indices

CAS Number: 890643-16-0

Roberta Costi

ABBV-744 - CAS# 2138861-99-9 48671 To test whether PK11007 alsoABBV 744 is a first in class, orally active and selective inhibitor of the BDII domain of BET family proteins with IC50 values range from 4 to 18 nM for BRD2, BRD3, BRD4 and BRDT. ABBV 744 is primarily metabolized by CYP3A4 with drug like properties enable the investigation of its antitumor efficacy and tolerability. Product information CAS Number: 2138861 99 9 Molecular Weight: 491. 55 Formula: C28H30FN3O4 Chemical Name: N ethyl 4 [2 (4 fluoro 2,6

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